Monday, 27 May 2024

Tumorigenesis-Tumor as a Condensate

 A tumor is like a condensate, analogous to the precipitation of de-differentiated cells. 

Differentiated cells, overcome some kind of energy barrier (Waddingtons epigenetic landscape) and de-differentiate from defined structure to an un-defined mass of cells.

These mass of cells lose their definitive interactions (epithelial mesenchymal transition) and condense to a solid mass.

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Targeting Cancer Stem Cells

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