Manifestation of Unity

 The manifestation of Unity (Wave function/Universal Energy Field) as multiplicity (Particles) in the double-slit experiment.

Fractals may be the mechanism via which Brahman/Universal energy field experiences the universe as Multiplicity via various minds (mind here is biological consciousness/thought emerging from the brain and is speculated to have a fractal structure or fractal function).

 Fractals are separated in time and space by Markov Blankets, which are most probably higher-order fractals. This occurs for energy-efficient propagation of information so that darker areas of destructive interference of waves are separated from lighter areas of constructive interference of waves resulting in particles as observed in the quantum double-slit experiment.

Cancer_Hypothesis

 Hypothesis of Cancer:

1.Probably the epigenome of a cell is modified by an oncogenic mutation. Phenotypic plasticity/tumor heterogeneity occurs in this process.

2. This modified epigenome overrides the inhibitory signaling of tumor microenvironment. Chaos ensues.

3. The above (2) breaks cell cell interactions leading to tumor cells release from primary site and spread i.e. invasion.

4. Altered epigenome leads to epithelial mesenchymal transition.

5. Tumor cells at secondary site  undergo mesenchymal epithelial transition due to restored epigenome in a new microenvironment.

6. As critical threshlod of oncogenic protein/signaling activity is breached (1) happens again.

7. A vicious cycle of tumor growth and spread ensues.

8. Altered expression/phenotype of tumor cells  containing oncogenic mutation occurs via phase transition.

9. The unpredictable component is how the epigenome is altered from a normal one to a cancerous one via the  oncogenic mutation.

The analogy with an Enzymatic Reaction:

Initiator-Oncogenic mutation, Epigenome alteration/Ist hit

Catalyst-Altered Tumor Microenvironment /2nd hit

Reactants-Normal cell

Product/s-Tumor cell