Saturday, 30 November 2019

Idealism|Physicalism

It is the human mind-body complex through which the truth of "idealism" is arrived at.
Idealism states that consciousness is the only reality.
Yes, BUT this reality can have different manifestations such as the physical body or other physical objects.
Humans arrive at truth not stones or rocks.
The idealists assert that consciousness is the "only"reality.
Idealism is directly of the 1st person|subject while physicalism is subject |object based. The object is manifestation.
The techniques via which the idealist conclusions are arrived at are practised by the human mind body complex i.e thinking , meditation etc. The human body (which is manifestation of this consciousness) is the truthful fact accepted by the physicalists.

Fundamentalism occurs when either idealists or materialists are UNABLE to recognize the perspective different from their own.


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Thursday, 28 November 2019

From Existentialism to Existential Enquiry

The existentialism of  Albert Camus etc asks- What is the Meaning of Existence ?
The existential enquiry of Vedanta asks- Who am I ?


https://en.wikipedia.org/wiki/Existentialism

Tuesday, 26 November 2019

Cancer-Chaotic oncogenic mutation-Epigenomic Alteration-Phase Transition-Metastasis

Hypothesis of Cancer:

1.Probably the epigenome of a cell is modified by an oncogenic mutation. Phenotypic plasticity/tumor heterogeneity occurs in this process.
2. This modified epigenome overrides the inhibitory signaling of tumor microenvironment. Chaos ensues.
3. The above (2) breaks cell cell interactions leading to tumor cells release from primary site and spread i.e. invasion.
4. Altered epigenome leads to epithelial mesenchymal transition.
5. Tumor cells at secondary site  undergo mesenchymal epithelial transition due to restored epigenome in a new microenvironment.
6. As critical threshlod of oncogenic protein/signaling activity is breached (1) happens again.
7. A vicious cycle of tumor growth and spread ensues.
8. Altered expression/phenotype of tumor cells  containing oncogenic mutation occurs via phase transition.
9. The unpredictable component is how the epigenome is altered from a normal one to a cancerous one via the  oncogenic mutation.

Analogy with an Enzymatic Reaction:

Initiator-Oncogenic mutation, Epigenome alteration/Ist hit
Catalyst-Altered Tumor Microenvironment /2nd hit
Reactants-Normal cell
Product/s-Tumor cell

Wednesday, 20 November 2019

Integration: Conscious Field---Gross matter

Universal Consciousness/Unifying Field/Equilibrium-----> Disrupted Equilibrium-----> Phase Transition/Multiple Vibrations=Abstract Mathematical Reality/Subtle matter/Mind---->Interactions of Vibrations through Resonance-------> Phase Transition of Vibrational energy to Gross Matter/Physical Reality.

Question-Homeostasis/Chaos

Are Homeostatic mechanisms and chaotic mechanisms inversely related to each other ?
Homeostatic mechanisms=Meditation=Nivritti/Inward stillness.
Chaotic mechanisms=Outward activity=Pravritti.

Thursday, 2 May 2019

Indeterminism and Determinism-An analogy with Scalar and Vector

Scalar-Having only magnitude not direction
Vector-Quantity having direction

Scalar - (minus) entropy/degree of disorder= Vector, OR, Scalar=Vector + Entropy

I will equate scalar to all the possibilities of occurrence, which when loses its disorder starts manifesting directionality and hence vector properties.

Under the above "indeterminism" is like a scalar, possessing the property of infinite possibilities and "determinism" is like a  vector showing directionality.

According to advaita (non-dual) psychology/philosophy -the absolute seen through the prism of time, space and causation becomes the relative  i.e. the Universe. Since there is an arrow of time in the classical world, cause and effect coming from this arrow of time, the universe is deterministic. Even in the quantum realm -the measurements are probability outcomes, in a range of possibilities.But are these possibilities infinite?

To me, intuitively, the absolute are the infinite fields of existence which have a range of possibilities of manifestation. The unmanifest is infinite, scalar, at equilibrium (possessing no directionality) and is what can be called free. Once a perturbation/disturbance occurs in this field, waves/particles arise which have defined properties (directionality). Intentionality has direction.


"Experience" and indeterminism:

This is tricky stuff! It is all speculative.

Indeterminism can only be "experienced" when the mind with all its intentionalities and uncontrolled thoughts is done away with by concentrating thought energy on the self-the unit feeling (feeling of being/equanimity/ a reflection of the universal equilibrium) . This results in focused thought energy  via which the illumination of awareness filters through, and helps one observe and experience reality as it is with its infinite possibilities . Can this be practically experienced? Limitedness due to uncontrolled thoughts dissolve away .

Duality/Multiplicity are pertubances in an equilibrium field and hence are directional i.e. vectorial while the undisturbed field at equilibrium is scalar.
As human beings,  under the influence of uncontrolled thoughts we will never experience indeterminism, but focus the thought energy or attentional energy on this awareness mentioned above and one will experience infinite possibilities.

Tuesday, 30 April 2019

Homeostasis and Complexity

Biomolecules such as RNA,DNA,amino acids etc, arose in a sea of interacting molecules in a  primordial soup. This was followed by compartmentalization to separate out the biomolecules from their environment. This resulted in homeostasis i.e. regulated exchange of matter between systems and surroundings.

According to wikipedia- "In biology, homeostasis is the state of steady internal physical and chemical conditions maintained by living systems.[1] This dynamic state of equilibrium is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits (homeostatic range). Other variables include the pH of extracellular fluid, the concentrations of sodium, potassium and calcium ions, as well as that of the blood sugar level, and these need to be regulated despite changes in the environment, diet, or level of activity."

Why did complexity arise then ? To provide more and more regulation for a system in varying environments. This complexity , arose perhaps through phase transition.

Homeostasis regulation may be compared to an analog knob with different possible states of being.
With a fluctuating environment, this knob has to be regulated and complexity is the hand that regulates the knob by fine-tuning to the environment.

Breakdown of regulated complexity , results in breakdown of homeostasis as in diseases like cancer. In cancer regulated multicellular organization breaks down due to mutations in genes and perturbations in environment. How do mutations  in genes occur ? Probably , mutations occur denovo and get selected for survival. But why so ? Its a mystery. The cancer seems to survive at the expense of the host.
Alternatively, environmental pertubations can cause mutations to occur in DNA resulting in higher risk for cancer.
https://www.pnas.org/content/99/25/15904

Increase in complexity results in highly evolved nervous systems. Probably these nervous systems evolved to regulate homeostasis. After a period of meditation (concentrated focus on a sound or words) I feel at calm and more relaxed. Probably meditation, by concentrating the mind, results in slowing the body metabolism resulting in greater regulation of homeostasis i.e. greater calm , lesser disturbed feelings.
https://www.ncbi.nlm.nih.gov/pubmed/25620166

Post meditation, one tends to observe things and processes through the lens of a calm , non-agitated mind.

Regulation and maintenance of homeostasis seems to me , one of the biggest drivers of evolution.