Showing posts from November, 2018

Cancer-Free energy principle

The free energy principle tries to explain how (biological) systems maintain their order (non-equilibrium steady-state) by restricting themselves to a limited number of states.[1] It says that biological systems minimise a free energy functional of their internal states, which entail beliefs about hidden states in their environment. (source wikipedia).

Is it possible that in cancer, during the process of tumorigenesis and metastases the free energy is maximised leading from order to disorder ?


I have written the following blog post and pinned it so that cancer researchers  who may come across this blog post can get ideas about why cancer occurs, how to think about cellular states in tumor formation and how they relate to the driver mutations and the tumor microenvironment. Hope it is useful.
The risk of developing cancer increases with age. The probabilities of errors in replication resulting in cancer causing mutation  occur because of the second law of thermodynamics . Error in DNA replication implies lack of  precision/accuracy in replication and an increase in randomness. This is exactly what the second law of thermodynamics predicts- an increase in entropy i.e randomness of the universe. With age the human dies, loss of physical organization of the human body occurs, matter gets converted to energy, and energy is returned back to the universe. So for treatment of cancer local entropy has to be decreased to regain back organization/precision accuracy. This means drugs …

What if:

Each particle is a vibration in a field. Particles interact with each other to give rise to higher orders of emergence.

 What if consciousness/sentience  is the vibration at each level, and interactions of vibrations at higher orders of emergence form complicated structures giving rise to consciousness as manifested through the living brain.

A plant is living and is different from a table made of wood, because the arrangement of atoms is different in a plant versus wood and plant/life interacts with the environment whereas wood does not.

Talking about memories : if they are encoded in the synaptic connections in the brain or within a neuron when the neuron dies the memory dies as structure is lost. But the atoms remain as combinations of vibrations in a field .

What if consciousness is  the vibratory energies at each level of emergence. In higher orders of emergence, vibrations/particles  interact with each other and through phase transition give rise to the brain and mind.