Dissolution of Markov Blankets

Can Markov Blankets be dissolved ? From the discrete to the continuous on a spectrum.
Can dissolution of Markov blankets cause disease by destroying distinct pathogen host boundaries?
Is the key to cellular homeostasis-maintaining a markov blanket between opposing signaling pathways ?
Is non duality a result of dissolved markov blankets ?
Is the experience of a discrete self  emergent from maintenance of markov blankets in continuous neuronal circuits ?

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